Gunther Enderlein published his concepts of microbial life cycles based on blood analysis observations in the book The Life Cycle of Bacteria Bakterien Cyklogenie . He theorized that the origin of every microbe was a tiny protein of plant origin that Enderlein called protits or colloids. Furthermore, he thought that specific stimuli caused this protein to polymerize from ball-like structures which he labeled symprotits and makrosymprotits into spermites, which Enderlein believed was a virus or prestage of bacteria. From this spermite viral phase , Enderlein reported that further development to a bacterium could take place, with final culmination into the fungi Aspergillus niger or Mucor racemosus.
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Gunther Enderlein published his concepts of microbial life cycles based on blood analysis observations in the book The Life Cycle of Bacteria Bakterien Cyklogenie . He theorized that the origin of every microbe was a tiny protein of plant origin that Enderlein called protits or colloids. Furthermore, he thought that specific stimuli caused this protein to polymerize from ball-like structures which he labelled symprotits and makrosymprotits into spermites, which Enderlein believed was a virus or prestage of bacteria.
From this spermite viral phase , Enderlein reported that further development to a bacterium could take place, with final culmination into the fungi Aspergillus niger or Mucor racemosus. Modern research conducted by Dr. Christopher Gerner, Ph. In addition, Enderlein did indeed observe some microscopic phenomena that seem to correlate to illness processes in human blood. However, his model of a life cycle of bacteria with a protein of plant origin protit as the starting point is no longer viable in light of the presented results.
Taking into account the limited knowledge and scientific techniques available to Enderlein decades ago, we can better understand how he came to his erroneous theories. The Life Of Prof. Enderlein Professor Dr. Guenther Enderlein was born in in Leipzig, located in eastern Germany. He studied natural science, physics and zoology at the University of Liepzig and graduated summa cum laude.
Following graduation, Enderlein served as an assistant at the Agricultural University in Berlin. He married in and two years later accepted a new position at the Zoological Museum in Stettin. From , he conducted research on his theory of bacterial life cycles, and published his findings in a book entitled Bacterien Cyklogenie The Life Cycle of Bacteria in During that period, he also was the director at the Zoological Institute and curator at the Berlin Zoological Museum.
In , Dr. Enderlein began his investigations of blood under the microscope. He used techniques available at that time, namely phase contrast and darkfield microscopy. These methods enabled him to observe both stained, dried blood and live blood preparations from healthy and sick animals and humans  . During his investigations, Enderlein observed many morphologies in the blood that he correlated to illnesses .
Enderlein reported seeing ball-like morphologies that he called protits, symprotits and makrosymprotits, depending on the increase in size .
Moreover, he observed string-like structures that he called filits, and string-like structures with a ball-like morphology on one end that he named spermites  . Ball-like morphologies significantly larger in size than symprotits and macrosymprotits were called mychit or thecit , while Enderlein named morphologies of many large, ball-like structures assembled in a row basit, phytit, rhabdit, linit and ascit, depending on the number arrayed .
Finally, the German researcher identified highly complex morphological structures as systases or petoharphen .
Enderlein observed these morphologies in the blood of patients suffering from various illnesses, and was able to correlate different morphologies to the progress of illnesses . As a result, he concluded that specific pathogenic structures develop in size and appearance depending on the progress of a particular illness Endobiosis .
Enderlein was able to make these structures microscopically invisible by adding alkaline solution to the blood preparation, an effect he could not observe by adding an acidic solution . This made him believe that he was observing a depolymerization reaction that resembles the reversing of the postulated upward development .
Because the identified structures were affected by an alkaline solution and not by an acidic solution, Enderlein concluded that a constant intoxification and high acidic load in the blood leads to ongoing physiological disturbances that manifests in the structures he observed in blood preparations.
The so-called mychit, thecit, basit, phytit, rhabdit, linit and ascit structures are morphologically similar to Syncrotis buccalis or Sclerothrix tubercolosis bacteria grown in culture when viewed with phase contrast microscopy . Due to this similarity, Enderlein concluded that these structures observed in blood preparations were living bacteria . Systase structures are morphologically comparable to fungus like Mucor racemosus or Aspergillus niger grown in liquid culture .
Therefore, Enterlein further inferred that systase structures observed in the blood of seriously ill patients are actually the fungi Mucor racemosus and Aspergillus niger . With this insight as background, it is possible to understand how Enderlein came to his conclusions. Isopathic Remedies Developed By Enderlein In his laboratory, Enderlein was able to reduce the morpological complexity of Mucor racemosus and Aspergillus niger preparations to ball-like structures with alkaline solution, much like he was able to do with systase morphologies in blood preparations .
He concluded that these fungi were the polymerization product of ball-like structures composed of a specific protein of plant origin, the so-called protit . Homeopathy attempts to restore disrupted functions and life processes of ill patients by prescribing a diluted substance that provokes symptoms in a healthy patient, that in large doses, are similar to those exhibited by the ill patient.
Homeopathic remedies are typically herbs or minerals. In contrast, isopathy is the treatment with the same substance that causes the illness, such as microbial pathogens or toxins, and additionally includes highly diluted mircrobes such as gonorrhea, scabies, syphilis or tubercolosis. Because Enderlein understood his remedies as lower, benign forms of the fungus Mucor racemosus and Aspergillus niger, he used the term isopathy to describe the preparations.
As a result, Enderlein hypothesized that spermites were viruses that infect mychits, which he believed were bacteria  . He further thought that spermites induced the degradation of bacterial cells mychit to smaller units, namely symprotits and macrosymprotits.
Enderlein described this as a sexual process that leads to the transition from pathogenic bacterial forms to non-pathogenic protein forms symprotit, macrosymprotit and viral forms spermites  . From these observations, Enderlein developed the idea that small protein units protits and symprotits from the fungi Mucor racemosus and Aspergillus niger should be able to induce the downgrading or degradation of pathologic morphologies that he observed in the blood samples of sick people   .
Consequently, Enderlein then produced isopathic remedies made from Mucor racemosus and Aspergillus niger that he thought provided the apathogenic structures protits, symprotits and spermites that supposedly could reduce pathogenic complex structures in the blood of patients suffering from various kinds of illnesses .
Therefore, Enderlein thought that all microbes possessed a natural development cycle that began with microscopically invisible, or very difficult to view, primitive protein phases protit, symprotit, makrosymprotit . These phases then proceeded to viral forms spermites and bacterial forms mychit, thecit, basit, phytit, rhabdit, linit and ascit , and finally culminated in a fungus Mucor racemosus or Aspergillus niger  .
This proposed upward development from primitive phases to bacteria to fungus was called probaenogenie or the complex of endobiosis by Enderlein, and he identified the Endobiont as the primary cause of disease . To sum up, he proposed that the development started with the most primitive form, a single protein or protit, which he thought was the primordial form of life and origin of every living being .
Enderlein also theorized that the unification or polymerization of many protits into ball-like structures known as symprotits or macrosymprotits led to the development of the primordial nucleus. Next, reserves of single living colloids symprotits assembled around the nucleus to provide the cell plasma, enabling the transformation into a cell to occur .
The protits could polymerize in different forms, creating new morphological structures such as spermite. Finally, as the cellular structures went through an upward development to more virulent forms due to a change in homeostasis. Enderlein proposed that the development of the highest forms to be pathogenic bacteria or fungi, which he believed to be Mucor racemosus or Aspergillus niger. Enderlein concluded that this upward development postulated as the life cycle of mircroorganisms is the cause of all forms of illness .
He proposed that the protit or Endobiont is present in every cell of the human body, and under a specific stimulus will progress through an upward development to higher pathogenic levels, culminating in a fungus   . He also theorized that this development was caused mainly by an improper diet that overfed the Endobiont with large amounts of protein and excessive nutrients . His basic understanding was that humans do not experience different kinds of illnesses, but one illness: the upward development of the Endobiont that leads to endobiosis.
According to the predisposition of the patient, the illness manifests different symptoms . To heal patients, Enderlein also theorized that the smallest elements from the life cycle of microbes protit, symprotit, macrosymprotit and spermite are completely apathogenic and useful for reversing endobiontic disease processes .
This represents the main principle on which he based his isopathic way of treating illnesses. Blood Analysis According To Enderlein Enderlein developed a diagnostic tool to examine the different morphologies observed in the blood of patients that he correlated to the progress of illnesses or stages of endobiosis .
By using darkfield and phase contrast microscopy, he examined stained, dried blood preparations and live blood. Guenther Enderlein. It reveals that Enderlein performed vital and dried blood examinations with darkfield and phase contrast microscopy, but he also used staining techniques as well.
Indeed, Enderlein only performed darkfield analysis on two specific phases — the spermite and filit phase. He also looked at many different parameters with stained preparations a fact often overlooked by Enderlein proponents who teach darkfield and determined the pathogencity of the so-called Endobiont .
It is important to understand why he developed this theory of life cycles based on his observations using microscopy. In , the Dutch researcher von Leeuwenhoek made the first observation of procaryotes, single cell living organisms such as bacteria.
In Schleiden and Schwann developed the theory that life is based on morphological units called cells. Until this time, no one had identified the functional unit of life the cell. In , Charles Darwin published his theories about he Origins of Species, and in the Czech monk Gregor Mendel proposed his laws of inheritance, although he did not know about genes or DNA.
In , Friedrich Miescher discovered nucleic acids, but it was not yet known that they were a matter of inheritance. From to , Gunther Enderlein developed his theory on the life cycles of bacteria. At that time, it was not known that humans have DNA and genes. DNA carries genes and regulates gene expression and is required to create proteins. In , Max Delbrock and Otto Hahn discovered that mutations are caused by changes of molecules.
This was a tremendous discovery because it provided a deeper understanding of the laws of heredity. In addition, the German scientist Erwin Schrdinger in made a theoretical deduction of the genetic code, explaining that it consisted of 3 bases that code in different composition the 20 amino acids required by the human body.
In , the German scientist Friedrich Sanger did the first complete sequencing of the protein insulin. About the same time, James Watson and Francis Crick proposed a model of the structure of DNA, which enabled scientists to understand how cells can divide and multiply the genetic information.
As previously mentioned, Gnther Enderlein published his theory in At that time, the scientific community believed that proteins were the basic unit of all living beings and the basis of heredity.
Therefore, Enderlein did not know about DNA and genetic information, and did not take it into account in his theory. In , Francis Jakob and Jaques Monod discovered that molecular switches exist on DNA, which means that genes expressed as proteins are tightly regulated.
In , the age of genetic technology began and it took only three years until the first genetically altered bacteria was created. In , A. Maxam, Walter Gilbert and Friedrich Sanger developed a rapid sequencing technique for long strands of DNA, and seven years later the first genetically produced medication, insulin, was completed.
In , science marked the official start of the human genome project, and in , the first eucaryote, a sheep named Dolly, was cloned. In , the first human genome project was completed  . How were these rapid advances possible? The answer is that science strongly depends on the techniques available at the time. Better techniques provide more complex ways to look into the human body.
For example, science knows today that humans have a 99 percent similarity to mice and human apes. However, the regulation and expression of genes makes a person look different than a mouse or an ape. The secret of life is not only located in the DNA but mainly the Proteom, the proteins made from the genes. How these proteins are made is regulated by other proteins.
This article is supported by the science and academia work group marked as Mid-importance. Enderlein was critical of the scientists of his day, because he felt they followed dogma, rather than presenting scientific evidence. I guess this article supports his contentions that the scientists who attacked him were not scientific. He must be rolling in his grave reading this biography. Perhaps he was taking his own medicine? Surely, the ultimate acid test of his theories is his own longevity! No serious scientist has any doubts about this.
A Modern Scientific Perspective On Prof. Dr. Enderlein’s Concept Of Microbial Life Cycles
Gunther Enderlein published his concepts of microbial life cycles based on blood analysis observations in the book The Life Cycle of Bacteria Bakterien Cyklogenie . He theorized that the origin of every microbe was a tiny protein of plant origin that Enderlein called protits or colloids. Furthermore, he thought that specific stimuli caused this protein to polymerize from ball-like structures which he labelled symprotits and makrosymprotits into spermites, which Enderlein believed was a virus or prestage of bacteria. From this spermite viral phase , Enderlein reported that further development to a bacterium could take place, with final culmination into the fungi Aspergillus niger or Mucor racemosus. Modern research conducted by Dr. Christopher Gerner, Ph.
Blood examination in darkfield according to Prof. Dr. Gunther Enderlein
Life[ edit ] Enderlein was born in Leipzig, the son of a teacher. He studied in Leipzig and Berlin and got his PhD in as a zoologist. He became professor in During the First World War he worked as a military surgeon major even though he was a biologist, as there were not enough physicians available at that time. He returned to Berlin in and remained there until After he became production manager in a small pharmaceutical company: Sanum that later became Sanum-Kehlbeck. He was also the publisher of a newspaper called Akmon.
Enderlein was a visionary thinker who made profound discoveries about the nature of chronic disease during his 60 year career. He wrote over scientific papers, was a journal editor, lectured internationally and founded the IBICA Institute for microbiological research into health. The phases of cyclogeny start from virus-sized particles, progressing to bacteria and then culminating a fungi. These microbial forms exist throughout the body and are symbiotic or pathogenic according to the conditions of the inner environment. By contrast, modern medicine is based on the monomorphistic view that microbes exist primarily in one form and mainly attack the body from the outside. Enderlein observed human microflora by using live blood under a darkfield microscope which enabled him to identify various types of degeneration.