BOCIO MULTINODULAR PDF

A goiter refers to an enlarged thyroid gland. Sometimes, a person can have a goiter that has multiple nodules or bumps on it, which is called a multinodular goiter. A toxic goiter is one that makes too much thyroid hormone, resulting in a condition called hyperthyroidism. Most thyroid nodules are harmless, but some can be cancerous. Scientists are still investigating the link between thyroid nodules and cancer.

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A few macrophages are also present. This pattern is associated with benign disease. Pigmented macrophages and few small epithelial cells which appear hypofuctioning small, hyperchromatic nuclei with scanty, denser cytoplasm. Fluid colloid, bland epithelial cells and histiocytes - Pigmented and vacuolated macrophages admixed with bland epithelial cells and bare nuclei.

Note the fluid colloid background. Pigmented and vacuolated macrophages, bland follicular cells - Pigmented macrophages with bland follicular cells and bare nuclei in the background.

They may be confused with lymphocytes which usually have a clearly identifiable peripheral rim of cytoplasm. Note the monolayered aspect of the cells and regular nuclei. Note the elongated hyperchromatic nuclei of fibroblasts in the upper left corner. This pattern is usually seen in FNAs from nodular goitres.

Bare nuclei - Numerous bare nuclei, probably derived from functional epithelial cells with abundant, clear and fragile cytoplasm arrow which exhibit a round nucleus with open chromatin and visible nucleolus.

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